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The subsequent literature never converged on DSIP being a sleep-inducing agent in any conventional sense, and its own principal investigators repeatedly noted effects that had nothing to do with sleep: stress tolerance, pain, withdrawal syndromes, chronobiological regulation

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(PubMed) McKenzie RC, Beckett GJ, Arthur JR

Although the percentage of patients using statins did not differ significantly between the two groups, the percentage tended to be lower in ALT responders than in ALT non-responders

Therefore, various APAP doses were tested to assess susceptibility to APAP-induced toxicity, aiming to investigate potential differences in tolerance between wild-type and hepsin / mice